产品货号:
Z19247
中文名称:
KDM2A抗体
英文名称:
Anti-KDM2A Antibody
产品规格:
50μl|100μl|150μl
发货周期:
1~3天
产品价格:
询价
| 抗体名称 | Anti-KDM2A Antibody |
| 指标别名 | CXXC8,F box protein FBL7,F box protein Lilina,F box/LRR repeat protein 11,FBL11,FBL7,FBXL11,JHDM1A,KDM2A,KIAA1004,LILINA,lysine (K) demethylase 2A,Lysine specific demethylase 2A |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | WB |
| 基因名称 | KDM2A |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | A synthetic peptide corresponding to a sequence of human FBXL11 (KRTFDLEEKLHTNKYNANFVTFMEGKDFNVEYIQR). |
| 实际分子量 | 133KD |
| 成分 | 500μg/mL antibody with PBS,0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt,-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | Lysine-specific demethylase 2A (KDM2A) also known as F-box and leucine-rich repeat protein 11 (FBXL11) is an enzyme that in humans is encoded by the KDM2A gene.This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif,the F-box.The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box),which function in phosphorylation-dependent ubiquitination.The F-box proteins are divided into 3 classes:Fbws containing WD-40 domains,Fbls containing leucine-rich repeats,and Fbxs containing either different protein-protein interaction modules or no recognizable motifs.The protein encoded by this gene belongs to the Fbls class and,in addition to an F-box,contains at least six highly degenerated leucine-rich repeats.This family member plays a role in epigenetic silencing.It nucleates at CpG islands and specifically demethylates both mono- and di-methylated lysine-36 of histone H3.Alternative splicing results in multiple transcript variants. |
| Uniprot ID | Q9Y2K7 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。 |
| 推荐稀释比 | Western blot(WB) 1:500~2000 |
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